The microseismic monitoring system used in the deep-buried diversion and drainage tunnels of Jinping-II hydropower station is introduced. An optimized layout of sensors working together with each other and keeping up with the movement of working face is proposed in line with the characteristic of tunnel excavation. The spatio-temporal evolution relation between microseismic event and rockburst is discussed. Results show that the active and quiet periods of microseismic activity coincide respectively with the frequent and rare rockburst-occurring periods, and the space distribution feature of microseismic events is similar to that of rockburst. The spatio-temporal evolution of microseismic events correlates well with the distribution features of rockburst. Therefore, it is possible and feasible to forecast rockburst disaster by the analysis and research on spatio-temporal evolution of microseismic events, which can provide scientific basis for rockburst prevention.