This paper introduces the design of intelligent optimizing anti - slide pile system based on MATLAB, and proposes the gross structure of the system, its main functions and especially the module of optimizing by combining BP network with simulated annealing genetic algorithm(SAGA). The main work of the system is to implement nonlinear optimization algorithm and to combine BP network with simulated annealing genetic algorithm. Eventually, the system ha s been applied to the optimum design of the prevention and cure of anti-slide pile in Xianglin Road of Yunnan province.