The integrated dispatching of large cascade reservoir groups on Yangtze River serves as the foundation of an optimal comprehensive benefit from basin water resources, and is also an important means to materialize the healthy Yangtze River strategy. To coordinate among the reservoirs, the main beneficial organizations  of the integrated dispatching were analyzed, and the restricting factors in the coordination were pointed out. A simple coordination frame comprising  decision-making, technology, and implementation was proposed for the integrated dispatching of large cascade reservoirs on Yangtze River.