The establishment of an integrated information system for office management based on Microsoft Solutions Framework (MSF) model is presented in line with model-development theories of software engineering. The iterative process of system demand collection, design, R&D, testing and deployment is introduced, and the application result is verified in terms of the software development efficiency, user ' s involvement and satisfaction. It is manifested that MSF model fits well with user ' s demand. The software development efficiency is improved, and the complexity of system building is greatly eased.