On the basis of the experiments of loading behaviors of the high efficiently prestressed concrete T-beam and the nonlinear characteristic of materials, an appropriate material constitutive relationship and a calculation model were selected, the behavior over loading process of the T-beam was simulated and analyzed by ANSYS. Comparison with the results of the finite element analysis and experiments, it is concluded that the simulation of deformation performance of the high efficiently prestressed concrete structures is feasible by the ANSYS. The result can provide the basis for the virtual test of prestressed concrete structure.