On the basis of the technique and theory of Embedded-GIS, ArcGIS Engine and GIS spatial analysis, and by combining the requirements of suddenly happened water pollution accident emergency response management system, we study the main content and method on suddenly happened water pollution accident emergency response system based on GIS technology, supported by the spatial database. This study can use the GIS technology for the water resource management so as to reduce the damage of water pollution influence. The study result has been used in Wanzhou stretch of the Three Gorges Reservior.