TOPMODEL(topography based hydrological model) is a model based on hydrological similarity, i.e., the grid having the same topographic index is the same unit to calculate the yield runoff, but it can not consider the spatial nonuniformity of information of the watershed topography and geomorphy, such as rainfall and topographic index statistics curve. So it cannot analysis the affection of the information on rainfall runoff. This paper attains the sub basin from the basin’s DEM and establishes a sub-basin TOPMODEL. The model considers the spatial nonuniformity of the rainfall and topography index curve. The sub basins TOPMODEL and TOPMODEL are used in Jiuzhou basin, the simulated result of the sub-basin TOPMODEL is better than TOPMODEL and the simulated results are more reasonable. It can also attain the discharge process of the different sub basins at the basin outlet and the percentage of the discharge of each sub basin in the basin outlet. Thus it can predicate the discharge process of basin outlet of the different rainfall combinations of the sub basin.