The Xinjiang Yarkant River basin is located at Tarim basin’s west edge. The supporting layer of the sluice is the powder sands. The structure of the sluice ground is characterized by loose sands, slight density and the weak medium water percolation soil stratum. There exist some questions about the foundation, including earthquake liquefaction, lower supporting capacity, the seepage stability, etc. A comprehensive sluice foundation treatment has been carried out in design stage, which includes the C20F150W6 steel bar concrete filling piles，the rotary spurt columns with high pressure，the vibration stone columns and the rigid C20F150W6 concrete cutoff wall,etc. To prove the design rationality and the construction feasibility, it is necessary to conduct the special experimental study to the foundation treatment. The article conducts the experimental study on sluice foundation treatment of the powder sand stratum, and the foundation treatment’s technical indexes in terms of reasonable construction techniques and the construction parameters corresponding to the measures have been confirmed. In a word, experimental study provided the reliable basis for the design or the construction and it has played a role in the optimization design function.