The grouting agents and grouting techniques used for cementchemical compound grouting treatment at fault zone F215 of Three Gorges Project are introduced and their effects after grouting are investigated and analysed in the paper.Practice demonstrated that to adopt cement chemical gr outing technique for treating the problems of geologic defect similar to fault z one F215 of TGP can meet the design requirements, and all technical indexes of grouting agent CW developed by Yangtze River Scientific Research Institute ar e excellent.