In order to expand the application of in-situ testing technology in soft soil projects in the Pearl River Delta and to verify the feasibility of using cross plate shear test result to calculate the shear strength of soft soil, we compared in-situ test results with indoor test results, and analyzed the application effects. We took the in-situ test and its engineering application in a soft soil fill slope in Zhuhai and a foundation pit engineering in Nansha, Guangzhou as engineering examples. Results unveil that in-situ test could well reflect the actual state of soft soil, and the shear strength parameter of soft soil calculated via vane shear test result is greater than those obtained by laboratory soil test. However,in Pearl River Delta region, the cohesion of soft soil calculated by method in Appendix J of Code for Foundation of Port Engineering(JTS 147-1—2010) exceeds empirical range, hence is not suitable for direct use in engineering design. We suggest that further theoretical research on the application of in-situ test data should be conducted to expand its application scope.