Drainage system and pressure reduction measures are usually adopted to treat the uplift of anti-seepage structure of water transfer project caused by long route and varying groundwater table. Check valve-drainage system in which reverse check valve plays a key role makes one of the best choice for its one-way flow performance. Existing reverse check valves have an inflexible opening and shutoff process, a poor long term performance, a meticulous construction operation, and must be accurately installed in a certain direction. To solve these problems, a novel reverse check valve based on differential pressure amplification is researched and developed in consideration of application conditions. The principle of opening and shutoff is improved; and new shutoff type and anti-clogging method are put forward. Opening and shutoff of the new check valve is only driven by amplified differential water pressure, and no other external force is needed, thus, it can be installed in every direction. Differential pressure amplification components and arc close structure are developed to improve the reliability and flexibility of opening and shutoff. Anti-clogging structure is designed and anti-fatigue problem is considered to ensure the long-term performance. The new reverse check valve can be widely used in the drainage system of canal, slope protection of dike and river course, groundwater table change belt of dam, water conveyance tunnel and other water-involving structures.