Single-objective evaluation method cannot effectively evaluate the rationality of water intake quantity and quota of fossil-fuel power station. In view of this, a multi-objective evaluation method based on projection pursuit was employed to evaluate the reasonability of water intake quantity and quota of fossil-fuel power stations in Changjiang River basin. Firstly, single-objective evaluation method was applied to evaluation and the result was analyzed. On this basis, multi-objective evaluation was conducted. Results show that the comprehensive score of Taicang fossil-fuel power station phase III is the highest and Nantong thermal power plant phase II is the lowest. This multi-objective evaluation method based on projection pursuit could effectively identify the information value of evaluation indexes, and give rational and objective assessment result. Four ranks (unqualified, qualified, good, and excellent) are recommended for the rating.